Guidelines for Controlled Trials of Drugs in Tension-Type Headache: Second Edition
If you’re one of the millions of headache sufferers around the world, more effective relief might be on the way in years to come. That’s because the International Headache Society has published new research guidelines intended to stimulate more research into headache treatment, and to provide researchers with guidelines to cut health risks associated with treatment.
The Clinical Trials Subcommittee of the International Headache Society published its first edition of the guidelines on controlled trials of drugs in tension-type headache in 1995. These aimed ‘to improve the quality of controlled clinical trials in tension-type headache’, because ‘good quality controlled trials are the only way to convincingly demonstrate the efficacy of a drug, and form the basis for international agreement on drug therapy’. The Committee published similar guidelines for clinical trials in migraine and cluster headache. Since 1995 several studies on the treatment of episodic and chronic tension-type headache have been published, providing new information on trial methodology for this disorder. Furthermore, the classification of the headaches, including tension-type headache, has been revised. These developments support the need for also revising the guidelines for drug treatments in tension-type headache. These Guidelines are intended to assist in the design of well-controlled clinical trials in tension-type headache.
Title: Guidelines for controlled trials of drugs in tension-type headache: Second edition
Authors: L Bendtsen, ME Bigal, R Cerbo, HC Diener, K Holroyd,C Lampl, DD Mitsikostas, TJ Steiner and P Tfelt-Hansen
From: Cephalalgia 30 (1): 1. (2010)