Posts Tagged ‘depression’

The unsuccessful antidepressant drug discovery process indicates a catastrophic systems failure

December 24, 2012

The failure of the antidepressant drug discovery process is systemic

From Journal of Psychopharmacology

Depression is widespread and accounts for approximately 12% of the total burden of non-fatal global disease. In the developed world around 25% of people can expect to experience this at some point in their lives. First line treatments for depression are mostly drugs based with antidepressants being the third most commonly prescribed medication in the United States. There are strong clinical and commercial pressures for new antidepressant drugs. However the prospects for this are reduced as several major pharmaceutical companies have abandoned research work whilst many others have decreased their research investment. It is argued these trends are indicative of a catastrophic systems failure. The aim of this paper is to explore the reasons why this hiatus has occurred and ways in which this knowledge can be used to help inform efforts to get the antidepressant drug discovery process moving forward once again.


Group therapy helps MS sufferers cope with depression

June 14, 2011

Evaluation of an adjustment group for people with multiple sclerosis and low mood: a randomized controlled trial

From Multiple Sclerosis

This new study finds group therapy helps MS sufferers cope with the disease and saves the NHS money. Offering Multiple Sclerosis sufferers emotional support through group therapy sessions could improve their quality of life and save the NHS almost £500 per patient it has been discovered. Researchers are now planning a larger multi-centre study into the issue to establish whether psychological therapy should be incorporated into the MS services currently provided by the NHS. It is recognised that many people with MS have problems with depression and anxiety and there are few treatments provided in NHS clinical services to address these.


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